10. Wear socks (or gloves) with special creams or petroleum jelly.
Exfoliating creams or lotions can help treat calluses, especially if they contain salicylic acid, urea, or ammonium lactate. In addition, skin-softening creams or petroleum jelly can also help soften the callus. Wearing socks or gloves after applying the creams can help seal in moisture for the callus on your feet or hands.